ESC-HFA 2023: Late-Breaking Science Video Collection

Published: 23 May 2023

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Overview

Get the most out of the new data from, Late-breaker host, Dr Harriette Van Spall and Dr James Januzzi wrap up of the most impactful trials and studies presented at Heart Failure 2023.

Delve into in-depth and critical discussions with Dr Van Spall in our thought-provoking Late-breaker Discussion series.

For concise and practical take-home messages for practice and cardiovascular research watch our 5-minute Expert Interviews conducted with investigators.

Watch our Behind the Heart Series to hear more from the personal perspectives of the investigators behind the top trials of HFA 2023. 

About the episode

Prof Domingo Pascual Figal (Hospital Clinico Universitario Virgen de la Arrixaca, SP) discusses the DAPA MODA study (NCT04707352). 

The study aimed to assess the effects of dapagliflozin on cardiac remodeling parameters, particularly LA geometry and function, and biomarkers reflecting pathophysiological pathways. Findings from HFA 2023 revealed that dapagliflozin administration in stable out-setting chronic HF patients with optimised therapy resulted in global reverse remodelling of cardiac structure, including reduced LA volumes, improved LV geometry and decreased NT-proBNP concentrations at 180 days.

Interview Questions:


1. What is known about SGLT2is' mechanism and study importance?
2. What is the study design, methodology, and outcomes?
3. What are the key findings?
4. What are the take-home messages?
5. How do the effects of dapagliflozin compare with other available treatments?

Faculty Biographies

Domingo Figal

Domingo Figal

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